2026-06-27T10:48:34Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1095652025-03-18T15:00:17Zcom_20.500.14352_14col_20.500.14352_15

Peñaloza Martínez, Eduardo Moreno Muñoz, Guillermo Aroca Crevillén, Alejandra Huertas, Sergio Vicent, Lourdes Rosillo, Nicolás Hidalgo, Andrés Bueno Zamora, Héctor José 2024-10-25T17:20:43Z 2024-10-25T17:20:43Z 2022-02-11 Peñaloza-Martínez E, Moreno G, Aroca-Crevillén A, Huertas S, Vicent L, Rosillo N, et al. Circadian rhythms in thrombosis and atherothrombotic events. Frontiers in bioscience (Landmark edition). NLM (Medline); 2022;27(2):51. 2768-6701 10.31083/j.fbl2702051 https://hdl.handle.net/20.500.14352/109565 https://doi.org/10.31083/j.fbl2702051 Biological circadian rhythms in living organisms are regulated by molecular clocks. Several of these clocks are present in blood vessels, peripheral tissues, and immune cells. There is strong evidence linking dysregulation of circadian rhythms to the development of cardiovascular disease. Dysregulation of circadian rhythms is believed to activate inflammatory processes at specific times of day, leading to an increased risk of thrombosis and atherosclerosis progression. Research into circadian clock genes and molecular networks has the potential to identify therapeutic targets to reduce cardiovascular risk. In this review, we summarize the evidence linking circadian rhythms to thrombosis and atherothrombotic events and discuss potential therapeutic implications. eng http://creativecommons.org/licenses/by/4.0/ open access Attribution 4.0 International Circadian rhythms in thrombosis and atherothrombotic events journal article