2026-06-27T15:23:16Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/1106902025-03-18T12:22:17Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Valencia Calvo, Marta author Durán Merinero, Alba author Lorenzo Aparicio, María Del Carmen author Gómez Gallego, María Del Mar author Sierra Rodríguez, Miguel Ángel author Eguillor, Beatriz author Esteruelas Rodrigo, Miguel Ángel author Oliván Escó, Montserrat author Oñate, Enrique 2024-11-18T11:46:01Z 2024-11-18T11:46:01Z 2020-01-15 Organometallics 2020, 39, 312−323 0276-7333 10.1021/acs.organomet.9b00693 https://hdl.handle.net/20.500.14352/110690 pubs.acs.org https://pubs.acs.org/doi/10.1021/acs.organomet.9b00693 OsH6(PiPr3)2 has been used to selectively activate C−H, O−H, and C−C sigma bonds in nucleobases and nucleosides, including derivatives of 6-phenylpurine and 4-phenylpyrimidine, leading to cyclometalated mononuclear Os−trihydride complexes, in excellent yields and as single products. Additionally, OsH6(PiPr3)2 promotes the efficient dehydrogenative decarbonylation of primary alcohols in nucleosides having unprotected sugar moieties. The incorporation of OsH2Cl2(PiPr3)2 in the structure of cyclometalated Ir(III) and Rh(III) half-sandwich complexes derived from nucleosides allows the preparation of a class of heterobimetallic bioorganometallic complexes having at least one M−C bond. These methodologies could be used in the future as a way for the orthogonal functionalization of oligonucleotides eng Attribution-NonCommercial-NoDerivatives 4.0 International Osmium-promoted σ‑bond activation reactions on nucleosides journal article 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