2026-06-28T09:50:07Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1126602025-03-18T12:40:35Zcom_20.500.14352_14col_20.500.14352_15

Optical quality in vitro and in vivo of an extended depth-of-focus intraocular lens with isofocal design Fernández-Núñez, Sara Pérez-Sanz. Lidia Albarrán-Diego, César Garzón Jiménez, Nuria García Montero, María Gómez Pedrero, José Antonio Purpose The aim of this study is to compare optical quality results obtained in laboratory analysis (in vitro) versus clinical data (in vivo). Methods The optical quality of ISOPure intraocular lens was assessed both in vitro and in vivo using the modulation transfer function (MTF) for 3.0 and 4.5 mm pupil diameters. In vitro measurements were obtained using deflectometer NIMO TRF1504, while in vivo measurements were taken with OPD-Scan III in a set of patients implanted with this lens. Ray tracing techniques were used to determine the MTF and area under MTF curve (MTFa) from the measured wavefront for the isolated lens and for the whole eye. Results The MTF of the isolated lens obtained under both in vitro and in vivo conditions showed comparable results for both pupil sizes. However, differences were found when comparing the MTF of the whole eye with the lens implanted versus the MTF measured in vitro for 4.5 mm pupil size. Also, the MTFa defocus curve was compared with the defocus curve measured in vivo. Conclusion The defocus curve from the in vivo study aligns closely with the MTFa of the in vitro model, with a useful defocus range of 0.40D. Thus, it is possible to anticipate the visual results of the implanted isofocal lens by using measurements on an optical bench and conducting optical simulations. 2024-12-16T11:50:44Z 2024-12-16T11:50:44Z 2024-12-16T11:50:44Z 2024-07-24 journal article https://hdl.handle.net/20.500.14352/112660 0721-832X 10.1007/s00417-024-06590-y 1435-702X eng info:eu-repo/grantAgreement/AEI/Plan Estatal de Investigación Científica, Técnica y de Innovación 2021-2023/PID2021-122486OA-I00/ES/Diseño de algoritmo de decisión clínica en el proceso de selección del tipo de LIO a implantar para corregir la presbicia y cataratas Design of a clinical decision algorithm in the selection process of the type of IOL to be implanted to correct presbyo Fernández-Núñez, S., Pérez-Sanz, L., Gómez-Pedrero, J.A. et al. Optical quality in vitro and in vivo of an extended depth-of-focus intraocular lens with isofocal design. Graefes Arch Clin Exp Ophthalmol (2024). https://doi.org/10.1007/s00417-024-06590-y restricted access Springer