2026-06-08T04:19:50Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1134652025-03-18T12:11:48Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense
author
García Csaky, Aurelio
author
Roscales García, Silvia
2025-01-09T11:07:10Z
2025-01-09T11:07:10Z
2019-10
Adv. Synth. Catal. 2020, 362, 111
1615-4169
10.1002/adsc.201901009
https://hdl.handle.net/20.500.14352/113465
https://onlinelibrary.wiley.com/doi/full/10.1002/adsc.201901009
The synthesis of aromatic amines is a hot topic of continuous interest in chemistry. An exceptionally versatile three-component reaction that directly transforms inexpensive nitro compounds, boronic acids, and trialkyl phosphites into tertiary aromatic amines has been realized. The reaction tolerates alkyl and aryl substituents on the nitro and boronic acid moieties, as well as functionalized phosphites. No transition-metal catalysis is required. The method is orthogonal to other classical metal-catalyzed syntheses since it tolerates the presence of halogens, and also permits the synthesis of functionalized compounds such as alpha-amino ester derivatives.
eng
Transition-metal-free three-component synthesis of tertiary aryl amines from nitro compounds, boronic acids, and trialkyl phosphites
journal article
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URL
https://docta.ucm.es/bitstreams/c6126402-4cbd-4611-80a1-77e0bd69c085/download
File
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application/pdf
ASC-201901009-Revised.pdf
URL
https://docta.ucm.es/bitstreams/79ff68f2-21e6-4802-ac99-93e4f1f764a7/download
File
MD5
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text/plain
ASC-201901009-Revised.pdf.txt