2026-06-01T01:49:40Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1172782025-03-18T15:52:27Zcom_20.500.14352_14col_20.500.14352_15
Biological activity of Fe(III) aquo-complexes towards ferric chelate reductase (FCR)
Escudero, R.
Gómez Gallego, María Del Mar
Romano, S.
Fernández, I.
Gutiérrez Alonso, Ángel
Sierra, M.A.
López Rayo, S.
Nadal, P.
Lucena, J.J.
547
Química orgánica (Química)
23 Química
In this study we have obtained experimental evidence that confirms the high activity of aquo complexes III and IV towards the enzyme FCR, responsible for the reduction of Fe(iii) to Fe(ii) in the process of iron acquisition by plants. The in vivo FCR assays in roots of stressed cucumber plants have shown a higher efficiency of the family of complexes III and a striking structure-activity relationship with the nature of the substituent placed in a phenyl group far away from the metal center. The results obtained in this work demonstrate that all the aquo compounds tested interact efficiently with the enzyme FCR and hence constitute a new concept of iron chelates that could be of great use in agronomy.
Ministerio de Ciencia, Innovación y Universidades
Comunidad de Madrid
Depto. de Química Orgánica
Fac. de Ciencias Químicas
TRUE
pub
2025-01-30T12:31:41Z
2025-01-30T12:31:41Z
2012
journal article
VoR
https://hdl.handle.net/20.500.14352/117278
XXXX-XXXX
10.1039/C2OB06754D
eng
CTQ-2010-20414-C02-01/ BQU
CSD2007-00006
CCG07-UCM/PPQ-2596
info:eu-repo/grantAgreement/MEC//AGL2007-63756/ES/NUEVOS FERTILIZANTES DE QUELATOS Y COMPLEJOS DE MICRONUTRIENTES. RELACION ENTRE CARACTERISTICAS QUIMICAS Y EFECTIVIDAD. BIODEGRADABILIDAD Y EFECTO DE LOS FORTIFICANTES/
info:eu-repo/grantAgreement/MICINN//AGL2010-18048/ES/CORRECTORES BIODEGRADABLES DE DEFICIENCIAS DE FE, MN Y ZN. NUEVOS DISEÑOS Y TECNICAS DE EVALUACION/
Escudero, R., Gómez-Gallego, M., Romano, S., Fernández, I., Gutiérrez-Alonso, Á., Sierra, M. A., López-Rayo, S., Nadal, P., & Lucena, J. J. (2012). Biological activity of Fe(iii) aquo-complexes towards ferric chelate reductase (FCR). Organic and Biomolecular Chemistry, 10(11), 2272-2281.
open access
application/pdf
The Royal Society of Chemistry