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00925njm 22002777a 4500 dc Sastre Ibáñez, Marina author Martínez De La Casa Fernández-Borrella, José María author Rebolleda Fernández, Gema author Cifuentes Canorea, Pilar author Moreno, María Nieves author Morales Fernández, Laura author Sáenz Francés, Federico author García Feijoo, Julián author 2018-01-01 Purpose: To evaluate whether the new rim analysis software with spectral-domain optical coherence tomography (SD-OCT) shows advantages over the retinal nerve fiber layer (RNFL) thickness in patients with moderate myopia. Methods: In this prospective cross-sectional study, we studied 65 healthy subjects, 37 with spherical refractive errors in the range of -3 to -6 D (moderate, G1) and 28 with less than -3 D (low/non-myopic, G0). All patients were examined with Heidelberg Spectralis SD-OCT, including Glaucoma Premium Module Edition (GPME) software. With GPME, we analyzed the neuroretinal rim (Bruch membrane opening-minimum rim width [BMO-MRW]) and RNFL. Results: The average age of subjects was 30.2 ± 9.3 years for G0 and 29.9 ± 7.1 years for G1 (p = 0.903). Mean sphere was −0.5 ± 0.3 D (-1.25 to 0 D) G0 and -3.9 ± 0.3 D (-6.00 to -3 D) G1 (p<0.001). The RNFL thickness comparison between G0 and G1 showed a significantly lower thickness in G1 (p = 0.018). The BMO-MRW measurements were similar in both groups (p = 0.331). With the BMO-MRW examination, the number of sectors classified as pathologic per subject in G1 were significantly lower compared to RNFL analysis (p = 0.023). Conclusions: Ring analysis based on BMO-MRW measurements shows a lower rate of false-positives compared to RNFL thickness when studying healthy moderate myopic eyes and it would be advisable to take this into consideration when analyzing these patients. Sastre Ibáñez, M., Martínez De La Casa Fernández-Borrella, J. M., Rebolleda Fernández, G. et al. «Utility of Bruch Membrane Opening-Based Optic Nerve Head Parameters in Myopic Subjects». European Journal of Ophthalmology, vol. 28, n.o 1, enero de 2018, pp. 42-46. DOI.org (Crossref), https://doi.org/10.5301/ejo.5001022. 1120-6721 10.5301/ejo.5001022 https://hdl.handle.net/20.500.14352/12072 https://doi.org/10.5301/ejo.5001022 http://journals.sagepub.com/doi/abs/10.5301/ejo.5001022 Utility of Bruch membrane opening-based optic nerve head parameters in myopic subjects