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00925njm 22002777a 4500 dc López Montes, Alejandro author López Herraiz, Joaquín author Galve Lahoz, Pablo author España Palomares, Samuel author Vicente, Esther author Cal Gonzalez, Jacobo author Udías Moinelo, José Manuel author 2019 PeneloPET is a Monte Carlo simulation tool for positron emission tomography based on PENELOPE. It was developed by the Nuclear Physics Group at University Complutense of Madrid and its initial version was released in 2009. In this work, we present PeneloPET v3.0, which is now available precompiled for Microsoft Windows, MacOS and Linux OS. This new release includes improved simulations of the positron range in different materials and an accurate description of the decay cascades for many radioactive nuclei including the most common non-pure positron emitters used in PET. This enables the simulation of PET acquisitions with positron-gamma emitters. This release also includes many different fully-working examples, of both clinical and preclinical scanners, as well as several numerical phantoms. Due to the simplicity of the input the output files, and the installation process, PeneloPET v3.0 can be perfectly used not only for research, but also as an educational tool in class. 1095-7863 10.1109/NSS/MIC42101.2019.9059837 https://hdl.handle.net/20.500.14352/12421 https://doi.org/10.1109/NSS/MIC42101.2019.9059837 https://ieeexplore.ieee.org/ PeneloPET v3.0, an improved multiplatform PET Simulator