2026-06-28T20:22:29Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1246502025-10-09T00:06:56Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense
author
Molina Fernández, Antonio Jesús
author
Hidalgo Agudo, Yumar
author
Ayllón Alonso, Elena María
author
Mena García, María Banesa
2025-10-08T09:59:02Z
2025-10-08T09:59:02Z
2025-09-30
Molina-Fernández, A.J, Hidalgo-Agudo, Y, Ayllón-Alonso, E, Mena-García, B (2025). Neuroscience and Genetic: Can They Be a Faustian Bargain for Addictive Behaviours Research and Treatment?. International Journal of Research and Innovation in Social Science (IJRISS), 9(08), 7024-7031. https://doi.org/https://dx.doi.org/10.47772/IJRISS.2025.908000582
2454-6186
10.47772/IJRISS.2025.908000582
https://hdl.handle.net/20.500.14352/124650
https://dx.doi.org/10.47772/IJRISS.2025.908000582
This article investigates the intersection of neuroscience and genetics in understanding and treating substance use disorders (SUDs), questioning whether the emphasis on these fields constitutes a “Faustian bargain.” Advances in neuroscience have elucidated the neural mechanisms of addiction, such as changes in the mesolimbic dopamine system, while genetic research has identified heritable factors contributing to addiction. Despite these insights, there remains a disparity between scientific knowledge and effective clinical applications. The study was done by a systematic review using PRISMA guidelines. Peer-reviewed articles published between 2020 and 2024 were selected from databases such as PubMed, Scopus and ASSIA. Inclusion criteria required studies to focus on human populations and be available in full text. Boolean expressions guided the search, targeting studies on addiction, genetics, neuroscience, and treatment. The data collection and analysis were conducted independently by reviewers, ensuring reliability and consensus. Out of the reviewed studies, significant findings revealed the complexity of addiction as a biopsychosocial phenomenon. Neuroscientific and genetic advances have provided foundational knowledge but have yet to translate into substantial improvements in treatment strategies. Correlation-focused genetic studies highlight the need for caution in interpreting causality. Additionally, environmental factors, such as stress and social context, play crucial roles in addiction and recovery. In conclusion, this article emphasizes the urgent need to integrate neuroscience, genetics, and environmental factors into a comprehensive addiction treatment model. Greater focus on psychosocial support, applied research, and data-driven interventions is essential for advancing care and addressing the multifaceted nature of SUDs.
eng
Attribution-ShareAlike 4.0 International
Neuroscience and genetic: can they be a Faustian bargain for addictive behaviours research and treatment?
journal article
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URL
https://docta.ucm.es/bitstreams/2dbf2899-2c3d-4a30-9a45-8af128524527/download
File
MD5
fc71ace3a3c11c9ba7a82582abcc04fe
266191
application/pdf
7024-7031.pdf