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Docta Complutense author Assaf Balut, Carla author Garcia De La Torre, Nuria author Durán Rodríguez-Hervada, Alejandra author Bordiú, Elena author Valle, Laura Del author Familiar, Cristina author Valerio, Johanna author Jimenez, Inés author Herraiz Martínez, Miguel Ángel author Izquierdo Méndez, Nuria author Runkle De La Vega, Isabel Ana author De Miguel Novoa, María De La Paz author Montañez, Carmen author Barabash Bustelo, Ana author Cuesta, Martín author Rubio Herrera, Miguel Ángel author Calle Pascual, Alfonso Luis 2023-06-17T12:35:36Z 2023-06-17T12:35:36Z 2019-09-19 Assaf Balut, C., García De La Torre, N., Durán Rodríguez-Hervada, A. et al. «An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the “Fourth Trimester”». Journal of Clinical Medicine, vol. 8, n.o 9, septiembre de 2019, p. 1499. DOI.org (Crossref), https://doi.org/10.3390/jcm8091499. 2077-0383 10.3390/jcm8091499 https://hdl.handle.net/20.500.14352/12574 https://doi.org/10.3390/jcm8091499 https://www.mdpi.com/2077-0383/8/9/1499 An early antenatal dietary intervention could play an important role in the prevention of metabolic diseases postpartum. The aim of this study is to evaluate whether an early, specific dietary intervention reduces women’s cardiovascular risk in the “fourth trimester”. This prospective cohort study compares 1675 women from the standard-care group (ScG/n = 676), who received standard-care dietary guidelines, with the intervention group (IG/n = 999), who received Mediterranean diet (MedDiet)-based dietary guidelines, supplemented with extra-virgin olive oil and nuts. Cardiovascular risk was determined by the presence of metabolic syndrome (MetS) and insulin resistance syndrome (IrS) (HOMA-IR 3.5) at 12–14 weeks postpartum. MetS was less frequent in the IG (11.3 vs. 19.3%, p < 0.05). The intervention was associated with a reduction in the relative risk of having MetS: 0.74 (95% CI, 0.60–0.90), but not in the risk of IrS. When analyzing the presence of having one or more components of the MetS, the IG had significantly higher rates of having 0 components and lower rates of having ≥1 (p-trend = 0.029). An early MedDiet-based nutritional intervention in pregnancy is associated with reductions in postpartum rates of MetS. eng Atribución 3.0 España An Early, Universal Mediterranean Diet-Based Intervention in Pregnancy Reduces Cardiovascular Risk Factors in the “Fourth Trimester” journal article URL https://docta.ucm.es/bitstreams/de42b2c3-9560-440e-bfa7-4e3a2caa4a9e/download File MD5 2519daf76ead729664f622e871215ab1 1763357 application/pdf jcm-08-01499.pdf