2026-06-28T04:47:47Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1291252025-12-17T00:47:54Zcom_20.500.14352_14col_20.500.14352_15

Martínez Rodríguez, Natalia Barona Dorado, Cristina Martín-Arés, María Cortés Bretón Brinkmann, Jorge Martínez González, José María 2025-12-16T11:51:11Z 2025-12-16T11:51:11Z 2012-03 Martínez-Rodríguez N, Barona-Dorado C, Martín-Arés M, Cortés-Bretón-Brinkman J, Martínez-González JM. Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar. Med Oral Patol Oral Cir Bucal. 2012 Mar 1;17(2):e345-51. doi: 10.4317/medoral.17414. 1698-4447 10.4317/medoral.17414 https://hdl.handle.net/20.500.14352/129125 1698-6946 https://doi.org/10.4317/medoral.17414 22143691 https://pubmed.ncbi.nlm.nih.gov/22143691/ Objectives: To evaluate the anaesthetic properties and tolerance of articaine versus lidocaine at equal vasoconstrictor concentration. Study design: A total of 96 male and female patients who underwent surgical treatment of the lower third molar participated. Patients were randomly assigned to articaine hydrochloride with epinephrine 1:100,000 and lidocaine hydrochloride with epinephrine 1:100,000. The variables analysed were latency period, duration of anaesthetic effect, tolerance and adverse reactions. Results: Both the latency period and the duration of anaesthetic effect were greater for articaine, although the differences were not statistically significant. Latency: mean difference of 2.70 ± 2.12 minutes (95%CI of -1.51 minutes - 6.92 minutes). Duration: mean difference of -33 minutes 5 seconds ± 31 minutes (95% CI -1 hour 35 minutes - 29 minutes). There were 4 adverse events that did not require the patients to be withdrawn from the study. Conclusions: The anaesthetics in this study have very similar properties for use in surgery and have demonstrated a good safety and tolerability profile. eng http://creativecommons.org/licenses/by/4.0/ open access Attribution 4.0 International Evaluation of the anaesthetic properties and tolerance of 1:100,000 articaine versus 1:100,000 lidocaine. A comparative study in surgery of the lower third molar. journal article