2026-06-29T02:37:32Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1299782026-01-14T00:59:44Zcom_20.500.14352_14col_20.500.14352_15
SARS-CoV-2 RapidPlex: a graphene-based multiplexed telemedicine platform for rapid and low-cost COVID-19 diagnosis and monitoring
Torrente RodrÃguez, Rebeca Magnolia
Lukas, Heather
Tu, Jiaobing
Min, Jihong
Yang, Yiran
Xu, Changhao
Rossiter, Harry B
Gao, Wei
The COVID-19 pandemic is an ongoing global challenge for public health systems. Ultrasensitive and early identification of infection is critical in preventing widespread COVID-19 infection by presymptomatic and asymptomatic individuals, especially in the community and in-home settings. We demonstrate a multiplexed, portable, wireless electrochemical platform for ultra-rapid detection of COVID-19: the SARS-CoV-2 RapidPlex. It detects viral antigen nucleocapsid protein, IgM and IgG antibodies, as well as the inflammatory biomarker C-reactive protein, based on our mass-producible laserengraved graphene electrodes. We demonstrate ultrasensitive, highly selective, and rapid electrochemical detection in the physiologically relevant ranges. We successfully evaluated the applicability of our SARS-CoV-2 RapidPlex platform with COVID19-positive and COVID-19-negative blood and saliva samples. Based on this pilot study, our multiplexed immunosensor platform may allow for high-frequency at-home testing for COVID-19 telemedicine diagnosis and monitoring.
2026-01-13T08:07:45Z
2026-01-13T08:07:45Z
2026-01-13T08:07:45Z
2020-12-02
journal article
https://hdl.handle.net/20.500.14352/129978
XXXX-XXXX
10.1016/j.matt.2020.09.027
eng
5R21NR018271
NNX16AO69A
Rebeca M. Torrente-RodrÃguez, Heather Lukas, Jiaobing Tu, Jihong Min, Yiran Yang, Changhao Xu, Harry B. Rossiter, Wei Gao, SARS-CoV-2 RapidPlex: A Graphene-Based Multiplexed Telemedicine Platform for Rapid and Low-Cost COVID-19 Diagnosis and Monitoring, Matter, Volume 3, Issue 6, 2020, Pages 1981-1998, ISSN 2590-2385, https://doi.org/10.1016/j.matt.2020.09.027.
embargoed access
Elsevier