2026-06-01T01:26:11Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1303472026-01-16T00:51:05Zcom_20.500.14352_14col_20.500.14352_15

Side-to-side magnetic duodeno-ileostomy in adults with severe obesity with or without type 2 diabetes: early outcomes with prior or concurrent sleeve gastrectomy Gagner, Michel Almutlaq, Lamees Cadiere, Guy-Bernard Torres García, Antonio José Sánchez Pernaute, Andrés Buchwald, Jane Abuladze, David 616.33 Duodeno-ileostomy; Magnet anastomosis system; Magnetic compression anastomosis; Metabolic/bariatric surgery; Obesity; Sleeve gastrectomy; Type 2 diabetes. Ciencias Biomédicas 32 Ciencias Médicas Background: Conventional metabolic/bariatric surgical anastomoses with sutures/staples may cause severe adverse events (AEs). Objectives: The study aim was to evaluate the feasibility, safety, and effectiveness of primary and revisional side -to -side duodeno-ileostomy (DI) bipartition using a novel magnetic compression anastomosis device (Magnet Anastomosis System [MS]). Setting: Multicenter: private practices and university hospitals. Methods: In patients with body mass index ([BMI, kg/m (2) ] >= 35.0 to < 50.0 with/without type 2 diabetes [T2D] glycosylated hemoglobin [HbA1C > 6.5 %]), two linear MS magnets were delivered endoscopically to the duodenum and ileum with laparoscopic assistance and aligned, initiating magnet fusion and gradual DI (MagDI). The MagDI- after -SG group had undergone prior sleeve gastrectomy (SG); the MagDI + SG group underwent concurrent SG. AEs were graded by Clavien-Dindo Classification (CDC). Results: Between November 22, 2021 and May 30, 2023, 43 patients (88.0% female, mean age 43.7 +/- 1.3 years) underwent the study procedures. The MS met feasibility criteria of magnet device placement, creation of patent anastomoses confirmed radiologically, and magnet passage in 100.0% of patients. There were 64 AEs, most were CDC grade I and II, significantly fewer in the MagDI-after-SG group ( P < .001). No device -related AEs including anastomotic leakage, bleeding, obstruction, infection, or death. The MagDI-after-SG group experienced 6 -month mean weight loss of 8.0 +/- 2.5 kg ( P < .01), 17.4 +/- 5.0% excess weight loss (EWL). The MagDI + SG group had significantly greater weight loss (34.2 +/- 1.6 kg, P < .001), 66.2 +/- 3.4% EWL. All patients with T2D improved. Conclusions: In early results of a multicenter study, the incisionless, sutureless Magnet System formed patent, complication -free anastomoses in side -to -side DI with prior or concurrent SG. Depto. de Cirugía Fac. de Medicina TRUE pub 2026-01-15T14:02:54Z 2026-01-15T14:02:54Z 2024 journal article VoR https://hdl.handle.net/20.500.14352/130347 1550-7289 10.1016/j.soard.2023.10.018 1878-7533 eng Gagner M, Almutlaq L, Cadiere GB, Torres AJ, Sanchez-Pernaute A, Buchwald JN, Abuladze D. Side-to-side magnetic duodeno-ileostomy in adults with severe obesity with or without type 2 diabetes: early outcomes with prior or concurrent sleeve gastrectomy. Surg Obes Relat Dis. 2024 Apr;20(4):341-352. doi: 10.1016/j.soard.2023.10.018. Epub 2023 Nov 10. PMID: 38114385. Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ open access application/pdf ELSEVIER SCIENCE