2026-06-07T17:25:18Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1304792026-01-17T00:49:30Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense
author
Bentancourt Rossoli, Judith V.
author
Campero, Lucía María
author
Moré, Gastón
author
Soto-Cabrera, Agustina
author
Moore, Dadín P.
author
Morrell, Eleonora L.
author
Scioli, María V.
author
Basso, Walter
author
Hecker, Yanina Paola
author
Scioscia, Nathalia P.
2026-01-16T14:54:19Z
2026-01-16T14:54:19Z
2026
Bentancourt Rossoli, J. V., Campero, L. M., Moré, G., Soto-Cabrera, A., Moore, D. P., Morrell, E. L., Scioli, M. V., Basso, W., Hecker, Y. P., & Scioscia, N. P. (2025). Toxoplasma gondii and Neospora caninum in naturally infected synanthropic (Muridae) and wild (Cricetidae) rodents from Argentina. Parasitology international, 112, 103204. Advance online publication. https://doi.org/10.1016/j.parint.2025.103204
10.1016/j.parint.2025.103204
https://hdl.handle.net/20.500.14352/130479
1383-5769
https://doi.org/10.1016/j.parint.2025.103204
41349635
Rodents serve as reservoir hosts for many parasites, including the closely related intracellular protozoan parasites Toxoplasma gondii and Neospora caninum, which are regarded as major causes of abortion in ruminants. This study investigated T. gondii and N. caninum infections in synanthropic (Muridae) and wild (Cricetidae) rodents from rural areas in the Pampas Region, Argentina, using histological, serological, and molecular methods. We also genetically characterized T. gondii isolates. A total of 356 rodents were captured, comprising both murid (Mus musculus, Rattus norvegicus, R. rattus) and cricetid (Oxymycterus rufus, Necromys spp., Akodon azarae, Oligoryzomys flavescens, Calomys musculinus, C. laucha) species. Histological examination did not reveal tissue cysts of these parasites. However, antibodies for T. gondii and N. caninum were detected in 9.8 % (35/356) and 1.7 % (6/356) of the samples using the indirect immunofluorescent antibody test (IFAT). T. gondii DNA was detected by qPCR in brain samples from two of the 41 seropositive rodents. Multilocus PCR-RFLP revealed atypical T. gondii genotypes in both samples. N. caninum DNA was not detected by PCR in any sample. This study provides the first serological and molecular evidence of T. gondii and N. caninum in Cricetidae rodents from Argentina, including the first genotyping data. The detection of T. gondii DNA exclusively in wild rodents highlights the role of wildlife in parasite transmission.
eng
Toxoplasma gondii and Neospora caninum in naturally infected synanthropic (Muridae) and wild (Cricetidae) rodents from Argentina
journal article
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URL
https://docta.ucm.es/bitstreams/cd654680-6965-409b-a84d-3107c03981b3/download
File
MD5
2625b92f5f2f7996de49c7ff63a7b06a
571653
application/pdf
Toxoplasma.pdf