2026-06-08T11:07:04Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/131062023-08-27T21:19:51Zcom_20.500.14352_14col_20.500.14352_15

00925njm 22002777a 4500 dc Kolosovas Machuca, Eleazar Samuel author Cuadrado Conde, Alexander author Ojeda Galván, Hiram Joazet author Ortiz Dosal, Luis Carlos author Hernández Arteaga, Aida Catalina author Rodríguez Aranda, María del Carmen author Navarro Contreras, Hugo Ricardo author Alda, Javier author González Contreras, Francisco Javier author 2019-02-06 In this paper, we report a fast and easy method to detect histamine dihydrochloride using gold nanostars in colloidal aqueous solution as a highly active SERS platform with potential applications in biomedicine and food science. This colloid was characterized with SEM and UV–Vis spectroscopy. Also, numerical calculations were performed to estimate the plasmonic resonance and electric field amplification of the gold nanoparticles to compare the difference between nanospheres and nanostars. Finally, aqueous solutions of histamine dihydrochloride were prepared in a wide range of concentrations and the colloid was added to carry out SERS. We found SERS amplified the Raman signal of histamine by an enhancement factor of 1.0 × 10 7 , demonstrating the capability of the method to detect low concentrations of this amine molecule. 2079-4991 10.3390/nano9020211 https://hdl.handle.net/20.500.14352/13106 https://doi.org/10.3390/nano9020211 https://www.mdpi.com/2079-4991/9/2/211 Detection of Histamine Dihydrochloride at Low Concentrations Using Raman Spectroscopy Enhanced by Gold Nanostars Colloids