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00925njm 22002777a 4500 dc Islas, Fabián author Olmos, Carmen author Vieira, Catarina author De Agustín Loeches, José Alberto author Marcos Alberca, Pedro author Saltijeral, Adriana author Almería, Carlos author Rodrigo López, José Luis author García Fernández, Miguel Ángel author Macaya Miguel, Carlos author Pérez De Isla, Leopoldo author 2015-04-04 Background/Objectives Atrial fibrillation (AF) is the most common cardiac arrhythmia and is associated with a significantly high risk of stroke and systemic embolism. The aim of our study was to assess the association between left atrium (LA) mechanics measured by 3D wall-motion tracking (3DWMT) technology and the most common thromboembolic risk scores (CHADS2, CHA2DS2-VASc). Methods A total of 101 consecutive patients with permanent AF referred were included. Conventional bidimensional (2D) LA parameters, and LA mechanics by means of 3DWMT were studied. Association between LA 2D and 3DWMT parameters and both risk scores was evaluated as well as its correlation with every component of the score individually. Results Mean age was 78 ± 10 years. Mean CHADS2 was 2.7 ± 1.3 and mean CHA2DS2-VASc was 4.4 ± 1.7. Values of 2D and 3DWTM LA parameters were: 2D area 26.4 ± 9.7 cm2, 2D volume index 49.4 ± 10.1 mL/m2, 3DWMT left atrial emptying fraction (LAEF) 15.9 ± 8.4%, longitudinal strain 9.1 ± 4.5% and area strain 14.9 ± 8.8%. Linear regression analysis showed statistically significant correlation between LA longitudinal strain and LAEF with CHADS2 and CHA2DS2-VASc scores. For each 10% variation in longitudinal strain, CHADS2 and CHA2DS2-VASc scores change in 0.7 and 0.8 points, respectively. Conclusions Left atrial longitudinal strain and emptying fraction assessed by 3D WMT technology have correlation with both CHADS2 and CHA2DS2-VASc scores. Each 10% of variation in longitudinal strain represents a 0.7 and 0.8 points change in those risk scores. LA mechanics evaluation might provide additional value to risk scores and could be considered to be a predictor of stroke in patients with AF. Islas, F., Olmos, C., Vieira, C., De Agustín, J. A., Marcos-Alberca, P., Saltijeral, A., Almería, C., Rodrigo, J. L., García Fernández, M. A., Macaya, C., & Pérez de Isla, L. (2015). Thromboembolic risk in atrial fibrillation: association between left atrium mechanics and risk scores. A study based on 3D wall-motion tracking technology. Echocardiography (Mount Kisco, N.Y.), 32(4), 644–653. https://doi.org/10.1111/echo.12711 0742-2822 10.1111/ECHO.12711 https://hdl.handle.net/20.500.14352/131392 1540-8175 https://doi.org/10.1111/ECHO.12711 https://onlinelibrary.wiley.com/doi/10.1111/echo.12711 Thromboembolic risk in atrial fibrillation: Association between left atrium mechanics and risk scores. A study based on 3D wall-motion tracking technology