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00925njm 22002777a 4500 dc De Agustín Loeches, José Alberto author Carda, Rocío author Manzano, María del C. author Ruiz-Mateos, Borja author García-Rubira, Juan C. author Fernández Ortiz, Antonio Ignacio author Vilacosta, Isidre author Macaya Miguel, Carlos author 2007 The main risk factor for contrast nephropathy is the presence of poor renal function. Plasma creatinine level is not a reliable measure of renal function as its value could lie within the normal range despite the presence of significant nephropathy. The purpose of this study was to evaluate the creatinine clearance rate as a predictor of contrast nephropathy in patients with a normal plasma creatinine level. The study included 273 consecutive patients with non-ST elevation acute coronary syndrome (NSTEACS) and a normal plasma creatinine level at admission who underwent coronary angiography. Patients who developed contrast nephropathy had a lower creatinine clearance rate at admission (66.3 mL/min vs. 83.4 mL/min; P<.001). A creatinine clearance rate < 80 mL/min had a sensitivity of 81% for predicting contrast nephropathy. Creatinine clearance should be measured routinely in patients with NSTEACS who are scheduled for coronary angiography. de Agustín, J. A., Carda, R., Manzano, M.delC., Ruiz-Mateos, B., García-Rubira, J. C., Fernández-Ortiz, A., Vilacosta, I., & Macaya, C. (2007). Aclaramiento de creatinina y nefropatía por contraste en pacientes con creatinina normal [Creatinine clearance and contrast nephropathy in patients with normal creatinine levels]. Revista espanola de cardiologia, 60(7), 772–776. 1579-2242 10.1157/13108283 https://hdl.handle.net/20.500.14352/132000 https://doi.org/10.1157/13108283 17663862 https://www.sciencedirect.com/journal/revista-espanola-de-cardiologia Aclaramiento de creatinina y nefropatía por contraste en pacientes con creatinina normal