2026-06-27T22:40:42Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1327322026-02-24T01:01:39Zcom_20.500.14352_14col_20.500.14352_15

González Villacorta, Patricia M. López Moral, Mateo García-Madrid Martín De Almagro, Marta García Morales, Esther Alicia Tardaguila García, Aroa Lázaro Martínez, José Luis 2026-02-19T19:10:46Z 2026-02-19T19:10:46Z 2025-03-05 González-Villacorta PM, López-Moral M, García-Madrid M, García-Morales E, Tardáguila-García A, Lázaro-Martínez JL. Hyperspectral Imaging in the Healing Prognosis of Diabetes Related Foot Ulcers. A Systematic Review and Meta-Analysis. Microcirculation. 2025 Apr;32(3):e70005. doi: 10.1111/micc.70005. PMID: 40043002. 1073-9688 10.1111/micc.70005 https://hdl.handle.net/20.500.14352/132732 1549-8719 https://doi.org/10.1111/micc.70005 https://onlinelibrary.wiley.com/doi/full/10.1111/micc.70005 Objective The diagnostic capability of hyperspectral (HSI) imaging has been focused on the prognosis of wound healing in patients with peripheral artery disease and diabetic foot ulcers (DFUs). The aim of this study was to evaluate the performance characteristics of HSI to determine the pretest probability for the prognosis of DFU healing. Methods A systematic search was performed on the PubMed, Medline, and Cochrane databases to identify studies evaluating HSI in predicting the prognosis of DFUs. This study was registered with PROSPERO (CRD42023495391). All selected studies were evaluated using the STROBE guidelines to assess the reporting quality for observational studies. Meta‐DiSc software was used to analyze the collected data. Results Nine publications (142 participants) were evaluated for systematic review. The meta‐analysis included four publications examining the prospective diagnostic capability of HSI. Concerning the prognostic accuracy of HSI, it had a pooled sensitivity of 0.84 (0.75–0.9) and a specificity of 0.79 (0.66–0.88) for predicting DFU healing, as well as an odds ratio of 20.4, resulting in a positive likelihood ratio of 4.1 and a negative likelihood ratio of 0.2 (heterogeneity I2 = 0). Conclusions The meta‐analysis revealed promising prognostic capability of HSI for the healing of DFU. More randomized clinical trials need to be published as our results are based on only prospective and comparative studies. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ open access Attribution-NonCommercial-NoDerivatives 4.0 International Hyperspectral Imaging in the Healing Prognosis of Diabetes Related Foot Ulcers. A Systematic Review and Meta‐Analysis journal article