2026-06-29T07:36:22Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/1336962026-03-03T01:01:07Zcom_20.500.14352_14col_20.500.14352_15

Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia Úbeda D’Ocasar, Edurne Valera Calero, Juan Antonio Gallego Sendarrubias, Gracia María Fernández de las Peñas, César Arias Buría, José Luis Morales Cabezas, Matilde Arendt Nielsen, Lars Cigarán Méndez, Margarita 61 Fibromyalgia Neuropathic pain Chronic pain Sensitization Pressure threshold Ciencias Biomédicas 3299 Otras Especialidades Médicas We aimed to analyze potential correlations between S-LANSS and PainDETECT with proxies for pain sensitization, e.g., the Central Sensitization Inventory (CSI) and pressure pain hyperalgesia (construct validity), pain-related or psychological variables (concurrent validity) in women with fibromyalgia (FMS). One-hundred-and-twenty-six females with FMS completed demographic, pain-related variables, psychological, and sensitization outcomes as well as the S-LANSS and the PainDETECT questionnaires. S-LANSS was positively associated with BMI (r = 0.206), pain intensity (r = 0.206 to 0.298) and CSI score (r = 0.336) and negatively associated with all PPTs (r = −0.180 to −0.336). PainDETECT was negatively associated with age (r = −0.272) and all PPTs (r = −0.226 to −0.378) and positively correlated with pain intensity (r = 0.258 to 0.439), CSI (r = 0.538), anxiety (r = 0.246) and depression (r = 0.258). 51.4% of the S-LANSS was explained by PainDETECT (45.3%), posterior iliac PPT (0.2%) and mastoid PPT (5.9%), whereas the 56.4% of PainDETECT was explained by S-LANSS (43.4%), CSI (10.4%), and pain intensity (2.6%). This study found good convergent association between S-LANSS and PainDETECT in women with FMS. Additionally, S-LANSS was associated with PPTs whereas PainDETECT was associated with pain intensity and CSI, suggesting that both questionnaires assess different spectrums of the neuropathic and pain sensitization components of a condition and hence provide synergistic information. Esta investigación y los gastos de publicación (APC) fueron financiados por la Universidad Camilo José Cela, número de subvención MORQUACERMU Depto. de Enfermería Fac. de Enfermería, Fisioterapia y Podología TRUE pub 2026-03-02T17:34:29Z 2026-03-02T17:34:29Z 2022-03-06 journal article VoR https://hdl.handle.net/20.500.14352/133696 XXXX-XXXX 10.3390/biomedicines10030612 2227-9059 eng Úbeda-D’ocasar E, Valera-Calero JA, Gallego-Sendarrubias GM, Fernández-De-las-peñas C, Arias-Buría JL, Morales-Cabezas M, et al. Association of Neuropathic Pain Symptoms with Sensitization Related Symptomatology in Women with Fibromyalgia. Biomedicines. 2022;10(3). Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ open access application/pdf Multidisciplinary Digital Publishing Institute (MDPI)