2026-06-27T01:08:30Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/136982025-02-14T14:05:42Zcom_20.500.14352_14col_20.500.14352_15

Daza, Rafael González Bermúdez, Blanca Cruces, Julia Fuente del Rey, Mónica de la Plaza, Gustavo R. Arroyo Hernández, María Elices Calafat, Manuel Pérez Rigueiro, José Guinea, Gustavo V. 2023-06-17T13:31:59Z 2023-06-17T13:31:59Z 2019-04-08 1878-0180 10.1016/j.jmbbm.2019.03.031 https://hdl.handle.net/20.500.14352/13698 https://www.sciencedirect.com/science/article/pii/S1751616118317934?via%3Dihub A comparative analysis of T-lymphocyte mechanical data obtained from Micropipette Aspiration (MPA) andAtomic Force Microscopy (AFM) is presented. Results obtained byfitting the experimental data to simple Hertzand Theret models led to non-Gaussian distributions and significantly different values of the elastic moduliobtained by both techniques. The use of more refined models, taking into account thefinite size of cells (sim-plified double contact and Zhou models) reduces the differences in the values calculated for the elastic moduli.Several possible sources for the discrepancy between the techniques are considered. The analysis suggests thatthe local nature of AFM measurements compared with the more general character of MPA measurementsprobably contributed to the differences observed. eng restricted access Comparison of cell mechanical measurements provided by Atomic ForceMicroscopy (AFM) and Micropipette Aspiration (MPA) journal article