2026-08-17T12:30:52Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/1389142026-07-29T00:28:00Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense
author
Domingo-Gómez, Alberto
author
Manocchio, Francesca
author
Morales Hernández, Diego
author
Arola-Arnal, Anna
author
Bravo, Francisca Isabel
author
Muguerza, Begoña
author
del Bas, Josep M.
2026-07-28T07:04:43Z
2026-07-28T07:04:43Z
2026
Domingo-Gómez, A., Manocchio, F., Morales, D., Arola-Arnal, A., Bravo, F. I., Muguerza, B., & del Bas, J. M. (2026). Photoperiod-dependent effects of (poly)phenol-rich extracts from seasonal fruits on the serum metabolome. Food Research International, 242, 119854. https://doi.org/10.1016/j.foodres.2026.119854
0963-9969
10.1016/j.foodres.2026.119854
https://hdl.handle.net/20.500.14352/138914
1873-7145
https://doi.org/10.1016/j.foodres.2026.119854
Seasonal rhythms are a recognised environmental factor affecting metabolism and health. In turn, phenolic compounds are recognised for their health-promoting properties and potential to influence biological rhythms. This work aimed to assess whether metabolic differences between seasons condition the response to dietary (poly)phenols. We exposed Fischer 344 male rats to short and long photoperiods simulating winter and summer, respectively. Eight different (poly)phenol-rich fruit extracts (FE) were administered, four obtained from spring-summer fruits and four of autumn-winter harvest fruits. A metabolomics-based approach was used for capturing systemic metabolic changes. Results showed a marked seasonal metabolic shift that conditions the response to FE. A common metabolic response to FE from autumn-winter fruits was identified accompanied by an anti-inflammatory pattern, suggesting that the effects were driven by shared seasonal characteristics of fruits rather than by the specific FE. Overall, (poly)phenols of seasonal fruits exert differential effects depending on the seasonally-conditioned metabolic state
eng
Attribution 4.0 International
Photoperiod-dependent effects of (poly)phenol-rich extracts from seasonal fruits on the serum metabolome
journal article
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7a414a8650ba5031ac57d84046cff603
10398394
application/pdf
Photoperiod-dependent.pdf