2026-06-29T07:49:40Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/192902023-08-27T15:37:45Zcom_20.500.14352_14col_20.500.14352_15
Genomic Plasticity of Vibrio cholerae.
Escudero García-Calderón, José Antonio
Mazel, Didier
vibrio cholerae
genome plasticity
superintegron
Medicina
Microbiología médica
Veterinaria
Microbiología (Veterinaria)
Biología molecular (Biología)
Ecología (Biología)
Microbiología (Biología)
32 Ciencias Médicas
3201.03 Microbiología Clínica
3109 Ciencias Veterinarias
3109.05 Microbiología
2415 Biología Molecular
2401.06 Ecología animal
2414 Microbiología
Vibrio cholerae is one of the deadliest pathogens in the history of humankind. It is the causative agent of cholera, a disease characterized by a profuse and watery diarrhoea that still today causes 95.000 deaths worldwide every year. V. cholerae is a free living marine organism that interacts with and infects a variety of organisms, from amoeba to humans, including insects and crustaceans. The complexity of the lifestyle and ecology of V. cholerae suggests a high genetic and phenotypic plasticity. In this review, we will focus on two peculiar genomic features that enhance genetic plasticity in this bacterium: the division of its genome in two different chromosomes and the presence of the superintegron, a gene capture device that acts as a large, low-cost memory of adaptive functions, allowing V. cholerae to adapt rapidly.
Unión Europea. FP7
Comunidad de Madrid
Centre National de la Recherche Scientifique/Institut Pasteur
French National Research Agency
Depto. de Sanidad Animal
Fac. de Veterinaria
Centro de Vigilancia Sanitaria Veterinaria (VISAVET)
TRUE
pub
2023-06-18T00:07:37Z
2023-06-18T00:07:37Z
2017-09
journal article
https://hdl.handle.net/20.500.14352/19290
1139-6709
10.2436/20.1501.01.295
eng
EVOTAR (282004)
(2016-T1/ BIO-1105)
(CNRS-UMR3525)
(ANR-10-LABX-62-IBEID); (ANR-12-BLAN-DynamINT)
open access
application/pdf
Springer