2026-08-20T02:10:54Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/231652024-09-02T13:41:46Zcom_20.500.14352_14col_20.500.14352_15

00925njm 22002777a 4500 dc Maçon, Anthony L. B. author Kim, Taek B. author Valliant, Esther M. author Goetschius, Kathryn author Brow, Richard K. author Day, Delbert E. author Hoppe, Alexander author Boccaccini, A. R. author Kim, Ill Yong author Ohtsuki, Chikara author Kokubo, Tadashi author Vallet Regí, María Dulce Nombre author Arcos Navarrete, Daniel author Fraile, Leandro author Salinas Sánchez, Antonio Jesús author Teixeira, Alexandra V. author 2015-02-11 The aim of this study was to propose and validate a new unified method for testing dissolution rates of bioactive glasses and their variants, and the formation of calcium phosphate layer formation on their surface, which is an indicator of bioactivity. At present, comparison in the literature is difficult as many groups use different testing protocols. An ISO standard covers the use of simulated body fluid on standard shape materials but it does not take into account that bioactive glasses can have very different specific surface areas, as for glass powders. Validation of the proposed modified test was through round robin testing and comparison to the ISO standard where appropriate. The proposed test uses fixed mass per solution volume ratio and agitated solution. The round robin study showed differences in hydroxyapatite nucleation on glasses of different composition and between glasses of the same composition but different particle size. The results were reproducible between research facilities. Researchers should use this method when testing new glasses, or their variants, to enable comparison between the literature in the future. Maçon, A. L. B., Kim, T. B., Valliant, E. M. et al. «A Unified in Vitro Evaluation for Apatite-Forming Ability of Bioactive Glasses and Their Variants». Journal of Materials Science: Materials in Medicine, vol. 26, n.o 2, febrero de 2015, p. 115. DOI.org (Crossref), https://doi.org/10.1007/s10856-015-5403-9. 0957-4530 10.1007/s10856-015-5403-9 https://hdl.handle.net/20.500.14352/23165 https//doi.org/10.1007/s10856-015-5403-9 https://link.springer.com/ A unified in vitro evaluation for apatite-forming ability of bioactive glasses and their variants