2026-06-27T12:21:49Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/239172023-08-25T23:13:56Zcom_20.500.14352_14col_20.500.14352_15

García Prieto, Concha Fernández Alfonso, María Soledad 2023-06-18T06:07:33Z 2023-06-18T06:07:33Z 2016-06-15 2072-6643 10.3390/nu8060370 https://hdl.handle.net/20.500.14352/23917 https://doi.org/10.3390/nu8060370 https://www.mdpi.com/2072-6643/8/6/370 Caloric restriction (CR) has proved to be the most effective and reproducible dietary intervention to increase healthy lifespan and aging. A reduction in cardiovascular disease (CVD) risk in obese subjects can be already achieved by a moderate and sustainable weight loss. Since pharmacological approaches for body weight reduction have, at present, a poor long-term efficacy, CR is of great interest in the prevention and/or reduction of CVD associated with obesity. Other dietary strategies changing specific macronutrients, such as altering carbohydrates, protein content or diet glycemic index have been also shown to decrease the progression of CVD in obese patients. In this review, we will focus on the positive effects and possible mechanisms of action of these strategies on vascular dysfunction. eng https://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España Caloric Restriction as a Strategy to Improve Vascular Dysfunction in Metabolic Disorders journal article