2026-06-27T15:23:32Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/343922023-07-14T02:51:14Zcom_20.500.14352_14col_20.500.14352_15

Moreno, David Giorgi, Giorgio Salas, Cristian Tapia, Ricardo 2023-06-19T13:45:57Z 2023-06-19T13:45:57Z 2013-11-26 1420-3049 10.3390/molecules181214797 https://hdl.handle.net/20.500.14352/34392 https://doi.org/10.3390/molecules181214797 https://www.mdpi.com/1420-3049/18/12/14797 In this report a short and efficient synthesis of the dibenz[b,f]oxepin framework through intramolecular SNAr and McMurry reactions is described. The diaryl ethers required for the McMurry reaction have been obtained in good yields under microwave-assisted conditions of the reaction of salicylaldehydes with fluorobenzaldehydes without catalysts. Application of an intramolecular McMurry reaction to the synthesized diarylethers using TiCl4/Zn in THF gave the target dibenzo[b,f]oxepin system in 53%–55% yields. eng https://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España New Short Strategy for the Synthesis of the Dibenz[b,f]oxepin Scaffold journal article