2026-06-29T09:38:44Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/352922024-04-09T12:30:59Zcom_20.500.14352_14col_20.500.14352_15
Klebsiella pneumoniae sequence type 11 from companion animals bearing ArmA methyltransferase, DHA-1 β-lactamase, and QnrB4
Hidalgo, Laura
Gutiérrez, Belén
Martínez Ovejero, Cristina
Carrilero Aguado, Laura
Matrat, Stephanie
Saba, Courage K S
Santos López, Alfonso
Thomas López, Daniel
Hoefer, Andreas
Suárez Rodríguez, Mónica
Santurde Sánchez, Gloria
Martín Espada, María Del Carmen
González Zorn, Bruno
Veterinaria
3109 Ciencias Veterinarias
Seven Klebsiella pneumoniae isolates from dogs and cats in Spain were found to be highly resistant to aminoglycosides, and ArmA methyltransferase was responsible for this phenotype. All isolates were typed by multilocus sequence typing (MLST) as ST11, a human epidemic clone reported worldwide and associated with, among others, OXA-48 and NDM carbapenemases. In the seven strains, armA was borne by an IncR plasmid, pB1025, of 50 kb. The isolates were found to coproduce DHA-1 and SHV-11 β-lactamases, as well as the QnrB4 resistance determinant. This first report of the ArmA methyltransferase in pets illustrates their importance as a reservoir for human multidrug-resistant K. pneumoniae.
Unión Europea. FP7
Ministerio de Ciencia e Innovación (MICINN)
Comunidad de Madrid
Centro de Vigilancia Sanitaria Veterinaria (VISAVET)
TRUE
pub
2023-06-19T15:04:58Z
2023-06-19T15:04:58Z
2013-09
journal article
https://hdl.handle.net/20.500.14352/35292
1098-6596
10.1128/AAC.00491-13
eng
EVOTAR (282004)
TRAIN-ASAP (289285)
BIO 2010-20204
PRI-PIBIN-2011-0915
BFU2011- 14145-E
VIGILANCIA SANITARIA-CM (S2009/AGR-1489)
restricted access
application/pdf
American Society for Microbiology