2026-06-08T03:26:04Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/361562024-07-09T14:25:11Zcom_20.500.14352_14col_20.500.14352_20

Geometry Induced Biofilm Formation Carpio Rodríguez, Ana María Espeso, David R. Enfermedades infecciosas Biomatemáticas 3205.05 Enfermedades Infecciosas 2404 Biomatemáticas Bacteria in aqueous environments usually gather to form aggregates called biofilms. In biofilms, cells display many behavioral differences from planktonic cells, such as a 1,000-fold increase in tolerance to antibiotics. Hospital-acquired infections are often caused by biofilm spread through medical systems. Design improvements hindering biofilm formation rely on identifying factors that favor their appearance. Geometry variations in medical flow circuits may trigger biofilm nucleation through vortical motion driving bacteria to walls. Detailed flow studies in mili and microfluidic devices support that observation. Once biofilm seeds are created, they proliferate forming filaments whose structure is again controlled by the geometry. Ministerio de Ciencia, Innovación y Universidades (España) Depto. de Análisis Matemático y Matemática Aplicada Fac. de Ciencias Matemáticas FALSE unpub 2023-06-19T16:04:41Z 2023-06-19T16:04:41Z 2015 conference paper https://hdl.handle.net/20.500.14352/36156 XXXX-XXXX eng FIS2011- 28838-C02 open access application/pdf