2026-06-26T16:58:34Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/59932024-04-16T17:15:02Zcom_20.500.14352_14col_20.500.14352_15

Paris, J.L. Vallet Regí, María Dulce Nombre 2023-06-16T15:15:32Z 2023-06-16T15:15:32Z 2020-01-06 1348-0634 10.1246/bcsj.20190346 https://hdl.handle.net/20.500.14352/5993 https://doi.org/10.1246/bcsj.20190346 https://www.ucm.es/valletregigroup https://www.journal.csj.jp/doi/pdf/10.1246/bcsj.20190346 Ultrasound has attracted much attention in recent years as an external stimulus capable of activating different types of nanomaterials for therapeutic application. One of the characteristics that makes ultrasound an especially appealing triggering stimulus for nanomedicine is its capacity to be non-invasively applied in a focused manner at deep regions of the body. Combining ultrasound with nanoparticles, different biological effects can be achieved. In this work, an overview of the four main types of inducible responses will be provided: inducing drug release, producing ultrasound-derived biological effects, modifying nanoparticle biodistribution and developing theranostic agents. Several examples of each one of these applications are presented here to illustrate the key concepts underlying recent developments in the discipline. eng open access Ultrasound-activated nanomaterials for therapeutics journal article