2026-06-08T04:38:16Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/601672024-09-24T14:03:44Zcom_20.500.14352_14col_20.500.14352_15

Skolnick, Jeffrey Kolinski, Andrzej Brooks, Charles L. Godzik, Adam Rey Gayo, Antonio 2023-06-20T20:22:15Z 2023-06-20T20:22:15Z 1993 0960-9822 10.1016/0960-9822(93)90348-R https://hdl.handle.net/20.500.14352/60167 http://www.cell.com/current-biology/fulltext/0960-9822(93)90348-R The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones. eng open access A method for predicting protein structure from sequence journal article