2026-06-08T03:25:18Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/601672024-09-24T14:03:44Zcom_20.500.14352_14col_20.500.14352_15

A method for predicting protein structure from sequence Skolnick, Jeffrey Kolinski, Andrzej Brooks, Charles L. Godzik, Adam Rey Gayo, Antonio 544 Química física (Química) The ability to predict the native conformation of a globular protein from its amino-acid sequence is an important unsolved problem of molecular biology. We have previously reported a method in which reduced representations of proteins are folded on a lattice by Monte Carlo simulation, using statistically-derived potentials. When applied to sequences designed to fold into four-helix bundles, this method generated predicted conformations closely resembling the real ones. Depto. de Química Física Fac. de Ciencias Químicas TRUE pub 2023-06-20T20:22:15Z 2023-06-20T20:22:15Z 1993 journal article https://hdl.handle.net/20.500.14352/60167 0960-9822 10.1016/0960-9822(93)90348-R eng open access application/pdf Elsevier