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oai:docta.ucm.es:20.500.14352/720622024-07-05T15:21:35Zcom_20.500.14352_14col_20.500.14352_15

Prieto Castañeda, Alejandro García Garrido, Fernando Díaz Norambuena, Carolina Escriche Navarro, Blanca García Fernández, Alba Bañuelos, Jorge Rebollar, Esther García Moreno, Inmaculada Martínez Máñez, Ramón Moya Cerero, Santiago de la Rodríguez Agarrabeitia, Antonia Ortiz García, María Josefa 2023-06-22T11:03:47Z 2023-06-22T11:03:47Z 2022-05-16 Prieto Castañeda, A., García Garrido, F., Díaz Norambuena, C. et al. «Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis». Organic Letters, vol. 24, n.o 20, mayo de 2022, pp. 3636-41. DOI.org (Crossref), https://doi.org/10.1021/acs.orglett.2c01169. 1523-7060 10.1021/acs.orglett.2c01169 https://hdl.handle.net/20.500.14352/72062 https://doi.org/10.1021/acs.orglett.2c01169 We have established an easy synthetic protocol for selectively developing all-orthogonal BODIPY trimers with unprecedented geometries on the basis of selecting methyl oxidation versus electrophilic formylation of key dimeric precursors. Photophysical characterization together with biological assays unraveled the most suitable BODIPY−BODIPY geometrical arrangements within the trimer, forcing them to serve as molecular platforms for the development of new, advanced heavy-atom-free photosensitizers for photodynamic therapy and phototheragnosis. eng https://creativecommons.org/licenses/by/3.0/es/ open access Atribución 3.0 España Development of Geometry-Controlled All-Orthogonal BODIPY Trimers for Photodynamic Therapy and Phototheragnosis journal article