2026-06-27T10:55:53Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/82022024-09-11T15:23:27Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Ji, Zichen author Miguel Díez, Javier De author Castro Riera, Christian Reynaldo author Bellón Cano, José María author Gallo González, Virginia author Girón Matute, Walther Iván author Jiménez García, Rodrigo author López De Andrés, Ana Isabel author Moya Álvarez, Virginia author Puente Maestu, Luis author Hernández Vázquez, Julio 2023-06-17T09:06:54Z 2023-06-17T09:06:54Z 2020-03-05 Ji, Z., Miguel Díez, J., Castro Riera, C. R. et al. «Differences in the Outcome of Patients with COPD According to Body Mass Index». Journal of Clinical Medicine, vol. 9, n.o 3, marzo de 2020, p. 710. DOI.org (Crossref), https://doi.org/10.3390/jcm9030710. 2077-0383 10.3390/jcm9030710 https://hdl.handle.net/20.500.14352/8202 https://doi.org/10.3390/jcm9030710 https://www.mdpi.com/2077-0383/9/3/710 Background: In chronic obstructive pulmonary disease (COPD), the “obesity paradox” is a phenomenon without a clear cause. The objective is to analyze the complications of COPD patients according to their body mass index (BMI). Methods: An observational study with a six-year prospective follow-up of 273 COPD patients who attended a spirometry test in 2011. Survival and acute events were analyzed according to the BMI quartiles. Results: A total of 273 patients were included. BMI quartiles were ≤24.23; 24.24–27.69; 27.70–31.25; ≥31.26. During the follow-up, 93 patients died. No differences were found in exacerbations, pneumonia, emergency visits, hospital admissions or income in a critical unit. Survival was lower in the quartile 1 of BMI with respect to each of the 2–4 quartiles (p-value 0.019, 0.013, and 0.004, respectively). Advanced age (hazard ratio, HR 1.06; 95% confidence interval, CI 1.03–1.09), low pulmonary function (HR 0.93; 95% CI 0.86–0.99), exacerbator with chronic bronchitis phenotype (HR 1.76; 95% CI 1.01–3.06), high Charlson (HR 1.32, 95% CI 1.18–1.49), and the quartile 1 of BMI (HR 1.99, 95% CI 1.08–3.69) were identified as risk factors independently associated with mortality. Conclusions: In COPD, low BMI conditions a lower survival, although not for having more acute events. eng Atribución 3.0 España Differences in the Outcome of Patients with COPD according to Body Mass Index journal article URL https://docta.ucm.es/bitstreams/793fc034-596d-4ed7-a16b-b34939940994/download File MD5 ad6aabc07b8a8454875f14dc09d5208e 435724 application/pdf jcm-09-00710-v2.pdf