2026-06-27T15:56:42Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/82432025-07-07T10:04:27Zcom_20.500.14352_14col_20.500.14352_15

00925njm 22002777a 4500 dc Palacios Ceña, María author Fuensalida Novo, Stella author Guerrero, Ángel L. author Cuadrado Pérez, María De La Luz author Ordás Bandera, Carlos author Madeleine, Pascal author Fernández de las Peñas, César author 2019-11-01 Background: Spatial changes in pressure sensitivity have been described in migraine and tension-type headaches. Our aim was to determine differences in the spatial distribution of pressure pain sensitivity of the temporalis muscle between cluster headache (CH) patients and headache-free controls. Methods: Pressure pain thresholds (PPTs) were determined over nine points covering the temporalis muscle in 40 men with episodic CH and 40 matched headache-free controls in a blinded fashion. Topographical pressure pain sensitivity maps were constructed based on interpolation of the PPTs. Patients were evaluated in a pain-free period (remission phase), at least 3 months from the last attack and without medication. Results: The analysis of covariance (ANCOVA) found significant difference between points (F = 21.887; P < 0.001) and groups (F = 24.416; P = 0.602), but not between sides (F = 0.440; P = 0.508). No effect of depression (F = 0.014; P = 0.907) or anxiety (F = 0.696; F = 0.407) was observed. A post-hoc analysis revealed: 1) lower PPTs at all points in patients than in controls, 2) an anterior-to-posterior gradient in patients but not in controls, with lower PPTs located in the anterior column. Large between-groups effects were shown in all points (standardized mean difference, SMD > 0.8). Conclusions: Bilateral pressure pain hypersensitivity to pressure pain in the temporalis muscle and an anterior-to-posterior gradient to pressure pain was observed in men with episodic CH.s. 1660-4601 10.3390/ijerph16214239 https://hdl.handle.net/20.500.14352/8243 https://doi.org/10.3390/ijerph16214239 https://www.mdpi.com/1660-4601/16/21/4239 Spatial Distribution of Temporalis Pressure Pain Sensitivity in Men with Episodic Cluster Headache