2026-06-27T12:38:34Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/910142024-05-14T00:00:58Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Zarco-Fernández, Sonia author García García, Aina author Sanz-Landaluze, Jon author Pecheyran, Christophe author Muñoz Olivas, Riansares 2023-11-30T17:24:25Z 2023-11-30T17:24:25Z 2018 Zarco-Fernández, S.; García-García, A.; Sanz-Landaluze, J.; Pecheyran, C.; Muñoz-Olivas, R. In vivo bioconcentration of a metal mixture by Danio rerio eleutheroembryos. Chemosphere 2018, 196, 87-94. 0045-6535 10.1016/j.chemosphere.2017.12.141 https://hdl.handle.net/20.500.14352/91014 https://doi.org/10.1016/j.chemosphere.2017.12.141 https://www.sciencedirect.com/science/article/pii/S0045653517321197 Exposure to heavy metals has represented one of the most serious health risks of environmental pollution over the last 50 years. Most of the bioconcentration studies that have been carried out to date explored only individual contaminants, unlike the real situations that occur in the environment. In this work, zebrafish eleutheroembryos were exposed to a mixture of CH3Hg(II), iAs(III), Ag(I) and Cd(II), and new BCFs were calculated and compared with those calculated from single metal exposures. In both cases, experimental conditions meet the OECD Test 305 conditions established for aquatic systems. In addition, spatial imaging obtained by laser ablation coupled to inductively plasma mass spectrometry (LA-ICP/MS), has been directly performed in these samples providing complementary information. The new BCF's have revealed some differences compared to single metal exposures when eleutheroembryos were exposed to the metal mixture, especially for iAs(III) and Cd(II). LA-ICP/MS images are in good agreement with the BFC's found, representing an interesting approach to get spatial distribution of metals that reinforces the toxicokinetic information. eng In vivo bioconcentration of a metal mixture by Danio rerio eleutheroembryos journal article 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URL https://docta.ucm.es/bitstreams/9386e49d-05a5-4ded-adf7-b2bdb2bbf354/download File MD5 066128a38c2f5facb3e1ed9aedaf8851 1500943 application/pdf Bioconcentration_of_metal_mixture.pdf