2026-06-08T11:03:41Zhttps://docta.ucm.es/rest/oai/requestoai:docta.ucm.es:20.500.14352/936442024-10-29T15:22:21Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense
author
Vintanel Moreno, Clara
author
Martínez González, José María
author
Martínez Rodríguez, Natalia
author
Meniz García, Cristina María
author
Leco Berrocal, María Isabel
2024-01-17T15:10:10Z
2024-01-17T15:10:10Z
2021-08-28
Vintanel-Moreno C, Martínez-González JM, Martínez-Rodríguez N, Meniz-García C, Leco-Berrocal I. Use of phentolamine mesylate in implant surgery: Analysis of adverse effects and haemodynamic changes. J Clin Med. 2021 Aug 28;10(17):3875.
2077-0383
10.3390/jcm10173875
https://hdl.handle.net/20.500.14352/93644
https//doi.org/10.3390/jcm10173875
https://www.mdpi.com/2077-0383/10/17/3875
The clinical application of phentolamine mesylate (PM) as an anaesthetic reversal agent has been documented in the paediatric population and in conservative dentistry, but no studies have been conducted regarding dental implant surgery. A prospective randomised study was conducted on 60 patients eligible for mandibular implant treatment, randomly divided between a control group (CG) and an experimental group (EG), to whom PM was administered. Haemodynamic changes, adverse effects and patient satisfaction were assessed. No statistically significant differences in haemodynamic changes and postoperative pain were found between CG and EG (p < 0.05), except for systolic blood pressure (SBP), which increased slightly in EG, without posing a risk to patients. There were no differences in the occurrence of adverse effects between the two groups, except for greater difficulty in chewing and biting (p < 0.05) in CG and greater pain in the injection area (p = 0.043) in EG. Among EG patients, 83.3% reported that they would request PM again for future dental treatment. The use of PM offers an alternative to implant surgery, thereby increasing patients’ quality of life without increasing the risks.
eng
Use of Phentolamine Mesylate in implant surgery: analysis of adverse effects and haemodynamic changes
journal article
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Use of phentolamine mesylate in implant surgery: Analysis of adverse effects and haemodynamic changes.pdf