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oai:docta.ucm.es:20.500.14352/943582024-07-17T00:06:08Zcom_20.500.14352_14col_20.500.14352_15

Pastor Vargas, Carlos Maroto, Aroa Díaz‐Perales, Araceli Villalba Díaz, María Teresa Casillas Diaz, Natalia Vivanco Martínez, Fernando Cuesta‐Herranz, Javier 2024-01-22T12:12:52Z 2024-01-22T12:12:52Z 2015 Pastor-Vargas C, Maroto AS, Díaz-Perales A, Villaba M, Casillas Diaz N, Vivanco F, Cuesta-Herranz J. Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding. Allergy. 2015 Aug;70(8):1024-7. doi: 10.1111/all.12646. Epub 2015 May 27. PMID: 25952012. 0105-4538 10.1111/all.12646 https://hdl.handle.net/20.500.14352/94358 1398-9995 https://doi.org/10.1111/all.12646 Food allergy is recognized as a major public health issue, especially in early childhood. It has been hypothesized that early sensitization to food allergens maybe due to their ingestion as components dissolved in the milk during the breastfeeding, explaining reaction to a food, which has never been taken before. Thus, the aim of this work has been to detect the presence of the food allergens in breast milk by microarray technology. We produced a homemade microarray with antibodies produced against major food allergens. The antibody microarray was incubated with breast milk from 14 women collected from Fundación Jiménez Díaz Hospital. In this way, we demonstrated the presence of major foods allergens in breast milk. The analysis of allergens presented in breast milk could be a useful tool in allergy prevention and could provide us a key data on the role of this feeding in tolerance induction or sensitization in children. eng http://creativecommons.org/licenses/by-nc-nd/4.0/ restricted access Attribution-NonCommercial-NoDerivatives 4.0 International Sensitive detection of major food allergens in breast milk: first gateway for allergenic contact during breastfeeding journal article