2026-06-27T23:49:37Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/948732025-03-18T16:02:56Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Rodríguez Artalejo, Antonio author Barahona Gomáriz, María Victoria author Llorente, Celia author Olivos Ore, Luis Alcides author Arribas Blázquez, Marina 2024-01-23T16:36:21Z 2024-01-23T16:36:21Z 2023-03-21 1573-9538 10.1007/s11302-023-09934-1 https://hdl.handle.net/20.500.14352/94873 1573-9546 https://link.springer.com/article/10.1007/s11302-023-09934-1 36941507 https://pubmed.ncbi.nlm.nih.gov/36941507/ María Teresa Miras Portugal devoted most of her scientific life to the study of purinergic signalling. In an important part of her work, she used a model system: the chromaffin cells of the adrenal medulla. It was in these cells that she identified diadenosine polyphosphates, from which she proceeded to the study of adrenomedullary purinome: nucleotide synthesis and degradation, adenosine transport, nucleotide uptake into chromaffin granules, exocytotic release of nucleotides and autocrine regulation of chromaffin cell function via purinoceptors. This short review will focus on the current state of knowledge of the purinoceptors of adrenal chromaffin cells, a subject to which María Teresa made seminal contributions and which she continued to study until the end of her scientific life. eng Attribution-NonCommercial-NoDerivatives 4.0 International María Teresa Miras Portugal: a pioneer in the study of purinoceptors in chromaffin cells journal article 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URL https://docta.ucm.es/bitstreams/945adcc5-d788-4c55-83be-5ebfdb7e4b5b/download File MD5 b3271007a2e1a6bf60fe62468893d8e8 534680 application/pdf Artalejo et al 2023 María Teresa Miras Portugal a pioneer in the study of purinoceptors.pdf URL https://docta.ucm.es/bitstreams/d866e175-1827-4ca3-a531-1d37cc1aaaa2/download File MD5 0ed12faa7d28f0828ff5031a29185ac8 31930 text/plain Artalejo et al 2023 María Teresa Miras Portugal a pioneer in the study of purinoceptors.pdf.txt