2026-08-16T14:18:15Zhttps://docta.ucm.es/rest/oai/request

oai:docta.ucm.es:20.500.14352/957782025-05-10T00:09:06Zcom_20.500.14352_14col_20.500.14352_15

Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics Revuelta, Julia Fuentes, Roberto Lagartera, Laura Hernáiz Gómez-Degano, María Josefa Bastida, Agatha García-Junceda, Eduardo Fernández-Mayoralas, Alfonso Fernández-Mayoralas, Alfonso A new strategy that enables a modular straightforward synthesis of heparan sulfate oligosaccharide mimics by the assembly of simple glycoamino acid building blocks is described. The coupling between units is readily carried out by an amidation reaction. Several glycoamino acid oligomers were prepared and their interaction with the FGF2 protein was analyzed. 2024-01-29T09:23:01Z 2024-01-29T09:23:01Z 2024-01-29T09:23:01Z 2018 journal article https://hdl.handle.net/20.500.14352/95778 1359-7345 10.1039/c8cc08067d 1364-548X eng info:eu-repo/grantAgreement/MAT2015-65184-C2-2-R info:eu-repo/grantAgreement/CTQ2015-66206-C2-1-R Revuelta J, Fuentes R, Lagartera L, Hernáiz MJ, Bastida A, García-Junceda E, et al. Assembly of glycoamino acid building blocks: a new strategy for the straightforward synthesis of heparan sulfate mimics. Chem Commun 2018;54:13455–8. https://doi.org/10.1039/C8CC08067D. restricted access Royal Society of Chemistry