2026-06-08T09:49:42Zhttps://docta.ucm.es/rest/oai/request
oai:docta.ucm.es:20.500.14352/998842024-02-14T01:00:41Zcom_20.500.14352_14col_20.500.14352_15
Docta Complutense author Vivas, David author Vivas Balcones, Luis David author Figuero Ruiz, Elena author Marín, Francisco 2024-02-07T10:50:18Z 2024-02-07T10:50:18Z 2023-09-01 Vivas D, Anguita-Gamez M, Ferrandis R, Esteve-Pastor MA, Echeverri M, Igualada J, et al. Prospective observational registry of perioperative and periprocedural management of antithrombotic therapy in "real world": the REQXAA study. Rev Esp Cardiol (Engl Ed). 2023;76:729-738 10.1016/j.rec.2023.03.003 https://hdl.handle.net/20.500.14352/99884 https://www.sciencedirect.com/science/article/abs/pii/S0300893223000532?via%3Dihub 36914025 https://pubmed.ncbi.nlm.nih.gov/36914025/ Estudio multicéntrico observacional prospectivo que analizó en 1.266 pacientes el manejo perioperatorio/periprocedimiento de los fármacos antitrombóticos. El estudio objetivó que en esta cohorte la adherencia a las recomendaciones fue baja y que, además, una mala adherencia a las recomendaciones se asoció a una mayor incidencia de eventos adversos, tanto trombóticos como hemorrágicos. Introduction and objectives: There is scarce real-world evidence on the management of perioperative antithrombotic treatment according to current recommendations. The aim of this study was to analyze the management of antithrombotic treatment in patients undergoing surgery or another invasive intervention and to assess the consequences of this management on the occurrence thrombotic or bleeding events. Methods: This prospective, observational, multicenter and multispecialty study analyzed patients receiving antithrombotic therapy who underwent surgery or another invasive intervention. The primary endpoint was defined as the incidence of adverse (thrombotic and/or hemorrhagic) events after 30 days of follow-up with respect to management of perioperative antithrombotic drugs. Results: We included 1266 patients (male: 63.5%; mean age 72.6 years). Nearly half of the patients (48.6%) were under chronic anticoagulation therapy (mainly for atrial fibrillation; CHA2DS2-VASC: 3.7), while 53.3% of the patients were under chronic antiplatelet therapy (mainly for coronary artery disease). Low ischemic and hemorrhagic risk was found in 66.7% and 51.9%, respectively. Antithrombotic therapy management was in line with current recommendations in only 57.3% of the patients. Inappropriate management of antithrombotic therapy was an independent risk factor for both thrombotic and hemorrhagic events. Conclusions: The implementation of recommendations on the perioperative/periprocedural management of antithrombotic therapy in real-world patients is poor. Inappropriate management of antithrombotic treatment is associated with an increase in both thrombotic and hemorrhagic events. eng Prospective observational registry of perioperative and periprocedural management of antithrombotic therapy in ‘‘real world’’: the REQXAA study journal article 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URL https://docta.ucm.es/bitstreams/10162277-c31f-4a55-a083-63ddac8f3d04/download File MD5 94b3a4d933434ebf7cda32da5e55f0ac 970654 application/pdf 2023-09 REC REQXAA principal.pdf