Sada Urmeneta, ÁngelaAgea Martínez, MarcMonteserín Martínez, EduardoAntúnez Conde, RaúlGascón Alonso, DafneArenas de Frutos, GemaNavarro Cuéllar, CarlosNavarro Cuéllar, Ignacio2024-09-052024-09-052022-09-29Sada-Urmeneta Á, Agea-Martínez M, Monteserín-Martínez E, Antúnez-Conde R, Gascón-Alonso D, Arenas-De-Frutos G, et al. Survival rate of odontogenic descending necrotizing mediastinitis. Our experience in last 5 years. Med Oral Patol Oral Cir Bucal. 2023 Jan 1;28 (1):e65-71.1698-444710.4317/medoral.25585https://hdl.handle.net/20.500.14352/107933Background Descending necrotising mediastinitis is one of the most lethal and least frequent forms of mediastinitis. It is a life-threatening infection most frequently originating from an oropharyngeal or odontogenic infection. Material and Methods A retrospective study of 6 patients diagnosed and treated for descending necrotising mediastinitis between 2015 and 2020 is reported. Results All patients were male, mean age of 34.83 years; 66% were smokers. 83% had an orocervical infection and 34% had initial mediastinal spread. All patients were treated initially with empirical broad-spectrum antibiotics and surgical drainage, with subsequent admission to the Intensive Care Unit; only one of them required tracheostomy. The mean hospital stay was 27.37 days. After a mean follow-up of 6 months, 100% of the cases had a complete recovery. Conclusions Early diagnosis and surgical treatment combined with improved life-support treatment in intensive care units and broad-spectrum antibiotic therapy leads to a decrease in associated mortality.engjournal article1698-6946https://doi.org/10.4317/medoral.25585https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9805333/open access617Odontogenic infectioncervical abscessacute mediastinitisdescending necrotizing mediastinitismortality rateCiencias Biomédicas32 Ciencias Médicas