Martínez, Manuel A.Greciano Raiskila, Elisa E.Cuéllar, JorgeValpuesta, José M.Sánchez Martín, Luis2023-06-172023-06-1720212079-499110.3390/nano11061457https://hdl.handle.net/20.500.14352/7477Herein, we describe the synthesis of highly emissive amphiphilic N-annulated PBI 1 decorated with oligo ethylene glycol (OEG) side chains. These polar side chains allow the straightforward solubility of 1 in solvents of different polarity such as water, iPrOH, dioxane, or chloroform. Compound 1 self-assembles in aqueous media by π-stacking of the aromatic units and van der Waals interactions, favored by the hydrophobic effect. The hypo- and hypsochromic effect observed in the UV-Vis spectra of 1 in water in comparison to chloroform is diagnostic of H-type aggregation. Solvent denaturation experiments allow deriving the free Gibbs energy for the self-assembly process in aqueous media and the factor m that is indicative of the influence exerted by a good solvent in the stability of the final aggregates. The ability of compound 1 to self-assemble in water yields globular aggregates that have been visualized by TEM imaging.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/journal articlehttps://doi.org/10.3390/nano11061457open access547amphiphileshydrophobic effectperylene bisimidesπ-stackingself-assemblyQuímica orgánica (Química)2306 Química Orgánica