Reche Gallardo, Pedro AntonioZhang, HongGlutting, John-PaulReinherz, Ellis L2023-06-202023-06-2020051367-480310.1093/bioinformatics/bti269https://hdl.handle.net/20.500.14352/50385EPIMHC is a relational database of MHC-binding peptides and T cell epitopes that are observed in real proteins. Currently, the database contains 4867 distinct peptide sequences from various sources, including 84 tumor-associated antigens. The EPIMHC database is accessible through a web server that has been designed to facilitate research in computational vaccinology. Importantly, peptides resulting from a query can be selected to derive specific motif-matrices. Subsequently, these motif-matrices can be used in combination with a dynamic algorithm for predicting MHC-binding peptides from user-provided protein queries. AVAILABILITY: The EPIMHC database server is hosted by the Dana-Farber Cancer Institute at the site http://immunax.dfci.harvard.edu/bioinformatics/epimhc/engjournal articlehttp://bioinformatics.oxfordjournals.org/content/21/9/2140.abstractopen access612.01757:004InmunologíaBiología molecular (Biología)Bioinformática2412 Inmunología2415 Biología Molecular