Nogueiras, RubénGarrido Novelle, MartaVázquez, MaríaLópez, MiguelDiéguez, Carlos2024-01-222024-01-222009Ruben Nogueiras, Marta G. Novelle, María Jesús Vazquez, Miguel Lopez, Carlos Dieguez, 2009. "Resistin: Regulation of Food Intake, Glucose Homeostasis and Lipid Metabolism", Pediatric Neuroendocrinology, S. Loche, M. Cappa, L. Ghizzoni, M. Maghnie, M.O. Savage978-3-8055-9302-1978-3-8055-9303-810.1159/000262538https://hdl.handle.net/20.500.14352/94360This work was supported by grants from Xunta de Galicia (C.D.: PGIDIT06PXIB208063PR and M.L.: GRC2006/66), Fondo Investigationes Sanitarias (M.L.: PI061700), Ministerio de Educacion y Ciencia (C.D.: BFU2008, M.L.: RYC-2007–00211, and R.N.: RYC-2008–02219), European Union (C.D.: Health-F2–2008–223713), and Mútua Madrileña (C.D. and M.L.). CIBER de Fisiopatología de la Obesidad y Nutrición is an initiative of ISCIII, Spain.Resistin has been identified as a hormone secreted by adipocytes that is under hormonal and nutritional control. This hormone has been suggested to be the link between obesity and type 2 diabetes. In rodents, resistin is mainly located and secreted from adipocytes, even though its expression was also found in several other tissues. However, in humans resistin is expressed primarily by macrophages and seems to be involved in the recruitment of other immune cells and the secretion of pro-inflammatory factors, although its role in insulin resistance cannot be ruled out. In addition to its role in glucose metabolism, resistin has been also involved in the control of hypothalamic and peripheral lipid metabolism and in the regulation of food intake. In this short review, we will summarize the most relevant findings of this hormone in rodentsengbook parthttps://doi.org/10.1159/000262538https://doi.org/10.1159/isbn.978-3-8055-9303-8restricted access577.17Bioquímica (Biología)2411.04 Fisiología Endocrina2403 Bioquímica