Fernández Vigo, José IgnacioFernández Aragón, SusanaBurgos Blasco, BárbaraLy Yang, FernandoDe-Pablo Gómez de Liaño, LucíaAlmorín Fernández-Vigo, IgnacioFernández Vigo, José AngelMartínez De La Casa Fernández-Borrella, José María2024-01-102024-01-102023Fernández-Vigo, J.I., Fernández-Aragón, S., Burgos-Blasco, B. et al. Comparison in conjunctival-Tenon’s capsule thickness, anterior scleral thickness and ciliary muscle dimensions between Caucasians and Hispanic by optical coherence tomography. Int Ophthalmol 43, 3969–3977 (2023). https://doi.org/10.1007/s10792-023-02798-910.1007/s10792-023-02798-9https://hdl.handle.net/20.500.14352/92355Purpose: To investigate the differences in the dimensions of the anterior ocular segment, and specifically in conjunctival-Tenon's capsule thickness (CTT), anterior scleral thickness (AST) and ciliary muscle thickness (CMT), between Caucasian and Hispanic subjects using swept-source optical coherence tomography (SS-OCT). Methods: Cross-sectional study including 53 Hispanic and 60 Caucasian healthy participants, matched by age, sex and refractive error, who underwent a complete ophthalmological examination. CTT, AST and CMT were manually measured in the temporal and nasal quadrants at 0, 1, 2 and 3 mm from the scleral spur using SS-OCT. Results: Mean age and refractive error were 38.7 ± 12.3 years and -1.05 ± 2.6 diopters, and 41.8 ± 11.7 years and -0.50 ± 2.6 diopters for the Hispanic and Caucasians, respectively (p = 0.165 and p = 0.244). The CTT was increased in the temporal quadrant in the Hispanic group in the three studied regions (CTT1, CTT2 and CTT3; being the means 223.0 ± 68.4, 215.3 ± 66.4 and 203.8 ± 67.1 µm versus 190.8 ± 51.0, 189.4 ± 53.2 and 187.4 ± 55.3 µm respectively; p < 0.001). Larger AST values were observed in the temporal quadrant in the Hispanic group (AST2: 559.8 ± 80.8 µm and AST3: 591.6 ± 83.0 µm) compared to the Caucasian group (520.7 ± 50.1 and 558.9 ± 54.7 respectively; p ≤ 0.022). No differences were observed in the nasal quadrant for CTT, AST1 and AST3 (p ≥ 0.076). No differences emerged in the CM dimensions (p ≥ 0.055). Conclusion: CTT and AST measurements were thicker in the temporal quadrant of Hispanic patients compared to Caucasians. This could have implications for the pathogenesis of different ocular diseases.engjournal article1573-2630https://doi.org/10.1007/s10792-023-02798-9https://link.springer.com/article/10.1007/s10792-023-02798-9restricted access611.84611.019CaucasianCiliary muscleConjunctivaHispanicScleral thicknessOftalmologíaTécnicas de la imagenAnatomía ocular3201.09 Oftalmología3314 Tecnología Médica2410.02 Anatomía Humana