Abellán, RosaGómez, ClaraOteo Calatayud, María DoloresScuzzo, GiuseppePalma Fernández, Juan Carlos2025-12-162025-12-162016-04-15Abellán R, Gómez C, Oteo MD, Scuzzo G, Palma JC. Short- and Medium-Term Effects of Low-Level Laser Therapy on Periodontal Status in Lingual Orthodontic Patients. Photomed Laser Surg. 2016 Jul;34(7):284-90. doi: 10.1089/pho.2015.40242578-547810.1089/pho.2015.4024https://hdl.handle.net/20.500.14352/129079Objective: The purpose of this study was to evaluate the short- and medium-term effects of low-level laser therapy (LLLT) applied in repeated doses in adults with a healthy periodontium treated by lingual orthodontic appliances. Background data: Plaque accumulation, in combination with difficulty in removing it in lingual orthodontic patients, can cause gingival inflammation. Methods: Twelve orthodontic patients scheduled for fixed lingual orthodontic treatment were selected. Clinical measurements [visible plaque index (VPI), bleeding on probing (BOP), and probing depth (PD), and collection of gingival crevicular fluid (GCF)], which was used to measure the levels of interleukin-1beta (IL-1β) and tumor necrosis factor alpha (TNF-α), was performed before bonding the lingual device, and at the short-term (1, 2, 3 months) and medium-term (12 months) follow-up appointments. For each patient, quadrant 1 or 2 was randomly chosen for irradiation by a diode laser (λ = 670 nm, 190 mW, 6.05 W/cm(2), 60 sec/ tooth) (Laser Group) and the contralateral quadrant was used as the Control Group. Results: In both studied groups, a slight worsening of the periodontal condition was observed, which was evident at the 3rd month follow-up and which was mainly at the lingual side in the Control Group. The levels of IL-1β in the GCF were significantly increased in the Control Group compared with the Laser Group at the 2nd and 3rd months after bonding. At the 12th month follow-up, an improvement of the inflammation was observed in both groups in the study. Conclusions: LLLT showed short-term effects by preventing a substantial increase in IL-1β levels. At medium-term follow-up, LLLT diminished VPI, BOP, and PD scores.engjournal article1557-8550https://dx.doi.org/10.1089/pho.2015.402427082031https://www.liebertpub.com/doi/10.1089/pho.2015.4024?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmedhttps://pubmed.ncbi.nlm.nih.gov/27082031/open access616.314-089.23:615.849.19Ciencias BiomédicasOdontología (Odontología)Aparatos y material odontológicosOrtodonciaLáseres32 Ciencias Médicas3201 Ciencias Clínicas3213.13 Ortodoncia-Estomatología3311.03 Instrumentos Para Odontología2209.10 láseres