Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology

García Porta, NeryRico Del Viejo, LauraMartín Gil, AlbaPintor Just, Jesús JerónimoCarracedo Rodríguez, Juan GonzaloGonzález Méijome, José Manuel2023-06-172023-06-172016-08García Porta, N., Rico Del Viejo, L., Martín Gil, A. et al. «Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratology». BioMed Research International, vol. 2016, 2016, pp. 1-9. DOI.org (Crossref), https://doi.org/10.1155/2016/1242845.2314-613310.1155/2016/1242845https://hdl.handle.net/20.500.14352/17686Purpose. To compare the ocular surface symptoms and signs in an adult population of silicone-hydrogel (Si-Hy) contact lens (CL) wearers with another modality of CL wear, overnight orthokeratology (OK). Materials and Methods. This was a prospective and comparative study in which 31 myopic subjects were fitted with the same Si-Hy CL and 23 underwent OK treatment for 3 months. Dry eye questionnaire (DEQ) was filled in at the beginning of the study and then after 15 days, 1 month, and 3 months using each CL modality. The tear quality was evaluated with noninvasive tear break-up time. Tear production was measured with Schirmer test. Tear samples were collected with Schirmer strips being frozen to analyze the dinucleotide diadenosine tetraphosphate (Ap4A) concentration with High-Performance Liquid Chromatography (HPLC). Results. After refitting with ortho-k, a reduction in discomfort and dryness symptoms at the end of the day (, ) was observed. No significant changes were observed in Ap4A concentration in any group. Bulbar redness, limbal redness, and conjunctival staining increased significantly in the Si-Hy group (, Kruskal–Wallis test). Conclusion. Discomfort and dryness symptoms at the end of the day are lower in the OK CL group than in the Si-Hy CL group.engAtribución 3.0 Españahttps://creativecommons.org/licenses/by/3.0/es/Differences in Dry Eye Questionnaire Symptoms in Two Different Modalities of Contact Lens Wear: Silicone-Hydrogel in Daily Wear Basis and Overnight Orthokeratologyjournal articlehttp://dx.doi.org/10.1155/2016/1242845https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022233/https://www.hindawi.com/journals/bmri/2016/1242845/open access617.7-089.243681.7.066617.71Dry eyeContact LensSilicone-hydrogel lensOrthokeratologyOcular surfaceLentes de contactoOptometríaÓptica oftálmica3311.11 Instrumentos ópticos2209.15 Optometría