Ryan Múrua, PabloVergas García, JorgeValencia La Rosa, JorgeCuevas, GuillermoGonzález Baeza, Alicia2024-04-252024-04-252023-11-24Ryan, P.; Dolengevich-Segal, H.; Ramos-Ruperto, L.; Cabello, A.; Sanchez-Conde, M.; Vergas, J.; Valencia, J.; Cuevas, G.; Sanz, J.; Curto-Ramos, J.; et al. Patterns of Sexualized Drug Use among Gay, Bisexual, and Other Men Who Have Sex with Men Living with HIV: Insights from a Comprehensive Study—The U-SEX-2 GESIDA 9416 Study. J. Clin. Med. 2023, 12, 7293. https://doi.org/10.3390/ jcm122372932077-038310.3390/jcm12237293https://hdl.handle.net/20.500.14352/103502Background: Sexualized drug use (SDU) has become a public health concern in recent years. This study aimed to estimate the prevalence of SDU in gay, bisexual, and other men who have sex with men living with HIV (HIV + GBMSM) in Madrid during 2019/2020 and compare it with data from 2016/2017 in order to detect changes in patterns. Methods: We analyzed the frequency of SDU in a sample of HIV + GBMSM attending HIV clinics, who participated in an anonymous online survey regarding sexual behavior and recreational drug use. The association between SDU, sexual risk behaviors, and STIs was evaluated. Results: This study included 424 HIV + GBMSM, with a mean age of 40 (10.43) years. Overall, 94% (396) reported being sexually active. Additionally, 33% (140) had been diagnosed with an STI within the previous year. Moreover, 54% (229) had used drugs in the last year, 25% (107) engaged in SDU, and 16% (17) reported engagement in slamsex. After adjusting for confounding factors, SDU was associated with STIs, fisting, unprotected anal intercourse, and having >24 sexual partners in the last year. According to the DUDIT test scores, 80% (81) probably had problematic drug use (≥6 points), and 8% (8) probable drug dependence (≥25 points). When comparing the U-SEX-1 (2016/2017) data with the U-SEX-2 (2019/2020) data, no significant differences were found in the proportion of participants practicing SDU or slamming. Conclusions: The prevalence of SDU among HIV + GBMSM has remained high in recent years and without significant changes. The risk of problematic drug use among those who practice SDU is high. We observed a clear association between SDU, high-risk sexual behaviors, and STIs.engAttribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/journal articlehttps://doi.org/10.3390/jcm1223729338068345https://www.mdpi.com/2077-0383/12/23/7293open access616.98VIHMSMHigh-risk sexual behaviorsHIVSexualized drug useChemsexSexually transmitted infectionsEnfermedades infecciosas3205.05 Enfermedades Infecciosas