Muñoz Úbeda, MónicaCarniato, FabioCatanzaro, ValeriaPadovan, SergioGrange, CristinaPorta, StefanoCarrera, CarlaTei, LorenzoDigilio, Giuseppe2023-12-122023-12-122016M. Muñoz Úbeda, F. Carniato, V. Catanzaro, S. Padovan, C. Grange, S. Porta, C. Carrera, L. Tei, G. Digilio, Chem. Eur. J. 2016, 22, 7716.0947-653910.1002/chem.201600962https://hdl.handle.net/20.500.14352/91192The redox microenvironment within a cell graft can be considered as an indicator to assess whether the graft is metabolically active or hypoxic. We present a redox-responsive MRI probe based on porous silica microparticles whose surface has been decorated with a Gdchelate through a disulphide bridge. Such microparticles are designed to be interspersed with therapeutic cells within a biocompatible hydrogel. The onset of reducing conditions within the hydrogel is paralleled by an increased clearance of Gd, that can be detected by MRI.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal articlehttps://doi.org/10.1002/chem.201600962restricted access544Química física (Química)2307 Química Física