Alonso Monge, Rebeca María Del MarCortés Prieto, IsabelRomán González, ElviraPla Alonso, Jesús2024-10-112024-10-112023-11-15Rebeca Alonso-Monge, Isabel Cortés-Prieto, Elvira Román, Jesús Pla, Morphogenetic transitions in the adaptation of Candida albicans to the mammalian gut, Microbes and Infection, Volume 26, Issue 3, 2024, 105253, https://doi.org/10.1016/j.micinf.2023.105253.1286-457910.1016/j.micinf.2023.105253https://hdl.handle.net/20.500.14352/1088862023 Acuerdos transformativos CRUECandida albicans is a pathobiont in humans that forms part of the mycobiota in healthy individuals and can cause different pathologies upon alterations of the host defenses. The mammalian gut is clinically relevant as this niche is the most common pool for bloodstream-derived infections. The ability of C. albicans to switch from yeast to hypha has been related to the commensal-to-pathogen transition and is, therefore, considered relevant in virulence. Recently, filaments have been implicated in the humoral response in the gut. C. albicans exhibits other morphologies that play different roles in pathogenicity and commensalism. This review focuses on the role of these morphological transitions in C. albicans proliferation and its establishment as a commensal in the mammalian gut, paying special attention to the transcription factors involved in their regulation.engAttribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/journal articlehttps://doi.org/10.1016/j.micinf.2023.105253open access615:54615.31CommensalismDimorphismWhite opaque transitionCandida albicansQuímica farmaceútica24 Ciencias de la Vida