Fasano, A.Herrero, Miguel A.López, J. M.Medina Reus, Elena2023-06-202023-06-2020102038-090910.1685/2010CAIM554https://hdl.handle.net/20.500.14352/43943A mathematical model to describe the process of formation of bone tissue by replacement of cartilage tissue is presented and discussed. This model is based on an absorption-diffusion system which describes the interaction of two key signalling molecules. These molecules characterize the dynamics of the transition zone between the cartilage and the bone tissue. Some experimental data are needed to estimate some model parameters. We discuss how our results are essentially unaffected by small variations, and in a particular case, not necessarily small variations in the experimental values.engjournal articlehttp://caim.simai.eu/index.php/caim/article/view/2010CAIM554http://www.simai.eu/open access51-76517.9519.87Growth plate dynamicsmathematical modelrobustnessBiomatemáticasEcuaciones diferencialesInvestigación operativa (Matemáticas)2404 Biomatemáticas1202.07 Ecuaciones en Diferencias1207 Investigación Operativa