Díaz Valle, DavidBenítez Del Castillo Sánchez, José ManuelCastillo Gómez, AlfredoSayagues, OctavioMoriche, Manuel2024-12-132024-12-131998-07-15Díaz-Valle, David, et al. «Endothelial Damage with Cataract Surgery Techniques». Journal of Cataract and Refractive Surgery, vol. 24, n.o 7, julio de 1998, pp. 951-55. DOI.org (Crossref), https://doi.org/10.1016/S0886-3350(98)80049-7.0886-335010.1016/S0886-3350(98)80049-7https://hdl.handle.net/20.500.14352/112594Purpose: To evaluate intraoperative endothelial damage after planned extracapsular cataract extraction (ECCE) with different capsulotomy techniques and phacoemulsification. Settings: San Carlos University Hospital, Castroviejo Institute, Madrid, Spain. Methods: In this prospective, randomized study, 60 patients with senile cataract scheduled for cataract surgery were divided into three groups of 20 each: Group 1 had phacoemulsification; Group 2, planned ECCE with continuous curvilinear capsulorhexis; and Group 3, ECCE with letter-box capsulotomy. Preoperatively and 3 months postoperatively, endothelial cell density, percentage of hexagonality, and the cell size variation coefficient were determined by contact specular microscopy; endothelial permeability was examined by anterior segment fluorophotometry and central comeal thickness, by ultrasonic pachymetry. Results were analyzed using the two-tailed Students t-test and analysis of variance. Results: In all three groups, endothelial permeability and cell loss increased significantly from the preoperative values, but there were no significant differences among the postoperative values. Mean cell loss was 11.8% in Group 1, 12.8% in Group 2, and 10.1% in Group 3. There were no differences between the preoperative and postoperative morphometric indexes. Postoperative pachymetric measurements were not significant. Conclusions: Endothelial response was not statistically significantly different among the surgical techniques, although endothelial damage was lower in Group 3, which could indicate a protective effect of the anterior capsule during cataract extraction. Endothelial barrier function remained disturbed despite the apparent morphological stabilization.engjournal articlehttps://doi.org/10.1016/S0886-3350(98)80049-7https://www.sciencedirect.com/science/article/pii/S0886335098800497restricted access617.7Oftalmología3201.09 Oftalmología